Tissue engineering for dentinal- pulp complex regeneration

Tissue engineering is the employment of biologic therapeutic strategies aimed to the replacement, repair, maintenance, and/or enhancement of tissue function that applies the principles of engineering and life science. The key ingredients for tissue engineering are stem cells, morphogen or growth factor that regulate their differentiation, and scaffold that constitute the microenvironment for their growth. Recently, there has been increasing interest in applying the concept of tissue engineering to regenerate dentinal pulp complex. The ultimate goal of a regenerative pulp treatment strategy is to reconstitute normal tissue continuum at the pulp dentin border.