Sfrp 4 as a biomarker for type 2 diabetes mellitus
International Journal of Development Research
Sfrp 4 as a biomarker for type 2 diabetes mellitus
Received 29th September, 2017; Received in revised form 04th October, 2017; Accepted 29th November, 2017; Published online 29th December, 2017
Copyright ©2017, Vasukidevi Ramachandran. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Recent evidence suggests that type 2 diabetes mellitus is a fast growing disease in world wide. The multiple complications are associated with T2DM.Serum secreted frizzled-related protein 4 (SFRP4) is a biomarker for T2DM. 503 patients with impaired glucose tolerance (IGT) and normal glucose tolerance (NGT) were investigated. Majorityof the patientsbelong to the low socio-economic groups between 40-70 years. These 503 participants, 407 females and 96 were normal females. ECG (Electrocardiogram) parameters were also in the study. SFRP4 levels were measured by ELISA kit SFRP4 levels were associated with a higher risk ofdeveloping type 2 diabetes (T2DM),attempt was to provide an outline for T2DM by SFRP4 estimation, will be an important tool to detect the early diabetes.
