Number Of Follicles At The Time Of Trigger And Mean Number Of Oocytes Retrieved: A Correlation Of Amh With Age, Mean Retrospective Study
International Journal of Development Research
Number Of Follicles At The Time Of Trigger And Mean Number Of Oocytes Retrieved: A Correlation Of Amh With Age, Mean Retrospective Study
Received 09th April, 2018 Received in revised form 21st May, 2018 Accepted 08th June, 2018 Published online 30th July, 2018
Copyright © 2018, Anitha Adaboina. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Introduction: For assisted reproductive technology [ART] to be successful, patients should be evaluated and correct ART should be selected. The ovary reserve is associated with oocyte quality and yield, it represents the reproductive potential of women. While various method are available to assess ovarian reserve, few methods are currently available to assess oocyte quality. The anti-mullerian hormone [AMH] is a member of transforming growth factor beta family. It is secreted by granulosa cells in the preantral and antral follicles in the ovaries.AMH plays a role in regulating ovarian activity. Methods: This prospective study of 75 patients were received antagonist protocol. AMH levels were measured and mean number of follicles at the time of trigger were counted. The patients were divided into four groups i.e very low [AMH <0.5], low [AMH 0.5 TO 1.1], normal [AMH 1.2 TO 3.5], High [AMH >3.5] 1. Results: In our observed study very low [ AMH<0.5]group showed mean number of follicles at the time of trigger is 2.3 and mean number of oocytes retrieved is 2.3, low [AMH 0.5 to 1.1]group showed 6.5 and 3.8, normal [AMH 1.2 to 3.5]group showed 7.5 and 6.0, high [AMH >3.5]group showed 16.5 and 14.4. The mean number of follicles at the time of trigger and mean number of oocytes retrieved correlates with AMH. Discussions: AMH can be used to predict the number of oocytes that can be collected during treatment. Basal AMH is used as an indicator to determine ovarian reserve. High AMH correlates with increased number of follicles and oocytes retrieved. Low AMH correlates with decreased number of follicles and decreased number of oocytes retrieved. Clinical Relevance: AMH is used as a marker to determine number of oocytes to be collected with controlled ovarian stimulation