Clinical aspects of children with cystic fibrosis and sars-cov-2 infection: a cohort study in a referral center in northeastern Brazil
International Journal of Development Research
Clinical aspects of children with cystic fibrosis and sars-cov-2 infection: a cohort study in a referral center in northeastern Brazil
Received 25th August, 2021; Received in revised form 03rd September, 2021; Accepted 06th October, 2021; Published online 23rd November, 2021
Copyright © 2021, Fábia Regina dos Santos et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Introduction: People with Cystic Fibrosis (CF) have a reduced life expectancy especially because of respiratory infections. Patients with CF are included in the group of people at higher risk of severe disease mediated by Coronavirus 19 (COVID-19). Therefore, the understanding of SARS-CoV-2 infection in children with CF is of fundamental importance to provide accurate guidance to parents for the risks of this disease. Objectives: To describe the clinical aspects of children with CF infected with SARS-Cov-2. Methodology: This is a cohort and descriptive study of children with CF from 0 to 18 years old. The study was based on the collection of nasopharyngeal secretions for the polymerase chain reaction/Sars-Cov-2 test. Results: Forty-three children with CF were evaluated. Of these, 17 (39.5%) were positive and 26 (60.5%) negative for Sars-Cov-2. Most children had a mild illness with 100% of them not hospitalized and 85.7% of hospitalized children recovered. Conclusion: The results suggest that children with CF infected with SARS-CoV-2 are symptomatic and despite requiring hospitalization, they have a favorable clinical course with a good prognosis in those who do not have preexisting severe lung disease.
