Liver metastasectomy in metastatic breast cancer: report of two cases and literature review
International Journal of Development Research
Liver metastasectomy in metastatic breast cancer: report of two cases and literature review
Received 10th February, 2021; Received in revised form 14th March, 2021; Accepted 21st April, 2021; Published online 30th May, 2021
Copyright © 2021, Rafael Martins Steffen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The breast cancer is the most frequent neoplasm in women, with only 22% 5-year survival in metastatic disease. The hepatic metastasectomy, when eligible, showed an impact of 82 months on overall survival in patients submitted to the procedure. However, it is an alternative treatment still debatable in literature. In this study, two reports of metastatic breast cancer with surgical approach are discussed. Patient 1 had liver metastasis of initially triple negative invasive ductal breast carcinoma, but with metastatic immunohistochemistry HER-2 positive. Patient 2 presented hepatic metastasis of invasive ductal carcinoma luminal A, with immunohistochemistry compatible. Both patients underwent segmental hepatectomy associated with systemic chemotherapy. The reports presented reproduce favorable scenarios for metastasectomy, with good outcome of patients. The literature review, associated with the data from the reports, demonstrate a significant impact on overall survival when a surgical approach was performed.
