Persistent metabolic syndrome and new cardiovascular risk markers in overweight or obese children and adolescents

Introduction: Confirmation of new markers that relate to metabolic syndrome evidence of cardiovascular disease prevention possibilities. Persistent metabolic syndrome is associated with new cardiovascular risk factors in children and adolescents are overweight or obese. Materials and Methods: Study of repeated measurements performed on Childhood Obesity Center April / 2009 to April / 2012, involving 133 children and adolescents. The evaluation took place at first and after 24 months. In both evaluations were performed anthropometry and diagnosis of metabolic syndrome, the second time the persistence of the syndrome was identified and then was verified its relationship with the new risk markers [fibrinogen, C-reactive protein ultrasensitive (CRP) , homocysteine and lipoprotein (a)]. Results: We observed persistence of the syndrome in 17.3% of evaluated. There was a positive correlation between homocysteine with waist circumference (p = 0.04) and negatively with HDL-C (p = 0.04) and positive of us-CRP with waist circumference (p = 0.01). Conclusions: Persistent metabolic syndrome was not associated with new cardiovascular risk markers, however there was positive correlation between the levels of hsCRP and homocysteine with waist circumference, negative relationship between HDL-C and hsCRP with lipoprotein (a) with waist circumference.