Major considerations on the use of plasma in eye aesthetics and the potential association with platelet rich plasma and coenzyme q10

The anatomy of the human face is complex. Particularly thin skin, elasticity and tone of the ligaments are also key. In this sense, Platelet Rich Plasma (PRP) contains numerous growth factors responsible for its effectiveness. Plasma is more uniform than ablative resurfacing lasers, including carbon dioxide (CO2) resurfacing lasers, as it does not depend on interaction with a particular target. In addition, as a potentiating and catalyzing effect, coenzyme Q10 (CoQ10) is a natural constituent of food and is also often used in foods and functional supplements. Objective: To present, through a systematic review, the main considerations of aesthetic ocular treatment using PRP, Plasma and Coenzyme Q10. Methods: Reviews, systematic reviews, prospective studies, retrospective studies, randomized, double-blind, placebo-controlled trials in humans with a recent publication were selected and analyzed. After criteria of literary search using the MeSH Terms that were cited in the item below under "Search Strategies", a total of 25 articles were collated and submitted for eligibility analysis and, after that, 18 studies were selected to compose the textual part of the manuscript and 12 to make the Systematic Review, following the rules - PRISMA. Major findings and conclusion: The use of Plasma can promote regeneration, lifting, wrinkling, improved sagging, collagen, elastin production, anti-inflammatory drugs, antibacterials, TDDS (transdermal delivery system), sterilization, skin remodeling. PRP has the potential to improve infraorbital dark circles in terms of color homogeneity in the region. PRP has been shown to promote wound healing and aid in facial lifting, volumetric skin, rejuvenation, skin regeneration and reconstruction, improved wrinkling. Ingestion of CoQ10 has limited seasonal viscoelastic deterioration and reduced some visible signs of aging. In addition, the results showed that stressed skin benefits from topical Q10 treatment, reducing free radicals and increasing antioxidant capacity.