Factors associated with drug-resistant tuberculosis in the state of maranhão, in the period from 2010 to 2015
International Journal of Development Research
Factors associated with drug-resistant tuberculosis in the state of maranhão, in the period from 2010 to 2015
Received 07th September, 2018; Received in revised form 14th October, 2018; Accepted 09th November, 2018; Published online 31st December, 2018
Copyright © 2018, Andréia Cristina da Silva Ribeiro et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Objective: To analyze the factors associated with drug-resistant tuberculosis (DRTB) in the State of Maranhão, from 2010 to 2015. Methods: An analytical cross-sectional study with DRTB cases of the Tuberculosis Special Treatment Information System (SITETB) using the model to identify associations. Estimated prevalence and 95% confidence intervals (95% CI). Results: Between 2010 and 2015, 124 (1.13%) cases of DRTB were reported. In the unadjusted analysis, the following were associated with BDRB: retreatment (95% CI = 1.71-3.84, OR = 2.56), closure because of non-cure (CI = 2.15-4.41, OR = (95% CI = 2.66-9.73, OR = 5.09), and use of illicit drugs (95% CI = 1.01-2.71, OR = 1.66), positive sputum smear microscopy. After adjusting for the model, the following were maintained: retreatment (95% CI = 1.05-2.48, OR = 1.61), closure for non-cure (95% CI = 2.01-4.35, OR = 2.96), and positive sputum smear microscopy (95% CI = 2.26-8.87, OR = 4.47). Conclusion: the prevalence of DRTB in Maranhão was low in relation to the country, however, entry by retreatment, closure due to non-cure and positive smear microscopy may be contributing to the maintenance of this rate.
