Invitro anticancer activity of coconut shell oil on breast cancer cell line

International Journal of Development Research

Volume: 
08
Article ID: 
12390
3 pages
Research Article

Invitro anticancer activity of coconut shell oil on breast cancer cell line

Dorathy Selva Jeba Pritha, S. and Karpagam, S.

Abstract: 

The ethanolic extract of Coconut shell oil were analysed for the anticancer activity against breast cancer cell lines. Coconut shells were collected and further processed for extract preparation. Breast cancer cell line was obtained from NCCS, Pune and was maintained in DMEM High Glucose media in 10% FBS, Penecillin (100 U/ml) and Streptomycin (100 µg/ml).The antiproliferative activity of Coconut shell oil were analysed by 0.5% 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-tetrazolium bromide (MTT) method. The highest non toxic concentration was observed at 125µg/ml concentration of ethanol extract of Coconut shell oil recorded in the cell line. These results showed the potential of Coconut shell oil as anticancer activity and further studies are necessary to analyse their mechanism and to isolate their anticancer compounds that is responsible for such activity.

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