Synchronous primary papillary carcinoma thyroid with ductal carcinoma breast: a rare case report

A 50 year old female admitted to R L jalappa Hospital, kolar, presented with synchronous primary tumours of the thyroid and breast. Pathological examination of a tissue sample following biopsy identified papillary carcinoma of the thyroid and invasive ductal carcinoma of the breast to provide a definitive diagnosis of synchronous primary tumors. The patient was healthy prior to diagnosis and the family history was non contributory. Upon admission, the size of the primary tumour biopsied, pathological diagnosis was an invasive carcinoma of the breast. A tumor measuring 3.0x2.5x2.0 cm was identified in the right side of the thyroid lobe, however, no further abnormalities were identified. Preoperative imaging included an ultrasound of the neck, which revealed a hypoechoic heterogeneity in the right lobe of the thyroid (size, 3.2x1.5 cm) exhibiting punc¬tate calcification. The patient was negative for clinical neck lymph node metastasis. A general physical examination did not indicate any abnormalities. A final preoperative diagnosis of invasive carcinoma of the right breast, as well as thyroid cancer was established. The patient underwent a modified radical mastectomy and total thyroidectomy and diagnosis confirmed.