A methodical qualitative and quantitative study of sublime “violet poison” w.s.r. to rasakarpura
International Journal of Development Research
A methodical qualitative and quantitative study of sublime “violet poison” w.s.r. to rasakarpura
Received 12th October, 2017; Received in revised form 26th November, 2017; Accepted 20th December, 2017; Published online 31st January, 2018
Copyright ©2018, Dr. Sushant Sud et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Rasakarpura is one of the Nirgandha murchana bheda of Parada. It appears as a white sublimate with chemical composition of mercuric chloride. The artificially prepared rasakarpura is commonly available in the market, prepared sublimed from metallic mercury, sulphuric acid and rock salt. This compound is widely used for many ayurvedic preparations. It is also known as Mercury bi-chloride or Mercury per-chloride. It appears as crystals or white granules or as powder; in the toxicology field it has a nickname “violet poison”. The work was taken up to fix up the standards for assessment of quality control over a Rasakarpura in order to interpret the pharmacokinetics and pharmacodynamics of the drug. The analysis of the drug Rasakarpura to establish standards in terms of Organoleptic characters, physico-chemical analysis, elemental analysis, XRD were carried out in IIT (SAIF), Powai, Mumbai and BTH, Bangalore. The result revealed that pH of the sample was more nearer to the neutral side. Particle size was 18 micron to 31 micron which may facilitate better absorption in the body. X-RD showed presence of HgCl2 as a main constituent along with other trace elements. These results were interpreted systematically and are presented in the paper.