Metabolic syndrome and its components are not associated with ABO blood groups

Objective: There are certain diseases which show strong association with ABO blood groups. No study has been performed for the association between ABO blood groups and metabolic syndrome. The aim of this study was to investigate the association between ABO blood groups and metabolic syndrome.
Patients and methods: A total of 300 subjects were enrolled to this cross-sectional study in two groups; 150 patients (according to the NCEP ATP III criteria) in metabolic syndrome group and 150 subjects in control group. All samples were examined for ABO blood groups by trypsin-polybren-citrate (TPC) technique. Frequency of ABO blood groups were determined in both groups. Waist circumference, systolic and diastolic blood pressure of all patients were recorded. Fasting glucose and serum lipid levels were measured. MedCalc 12.7 software program was used for statistical analyses.
Results: Chi square test results showed that frequency of blood groups were comparable in study and control groups (p>0.05). There was no association between ABO blood groups and metabolic syndrome (p>0.05). The frequencies of components of metabolic syndrome were comparable in all ABO blood groups (p>0.05).
Conclusion: In this case-control study, metabolic syndrome and its components are not associated with ABO blood groups.