Lipid accumulation product index predictor tool insulinic resistance undiagnosed in adolescents girls

Objective: To evaluate the predictive capacity of the lipid accumulation product in the detection of insulin resistance in female adolescents. Methods: A cross-sectional study was carried out with 113 adolescents from public schools, aged 10 to 19 years. The anthropometric, sociodemographic, hemodynamic and biochemical variables were evaluated. The waist height ratio, waist hip ratio and lipid accumulation product were determined through protocols described in the literature. The presence of insulin resistance was determined through HOMA-RI, using a cut-off point =3.16. Data analysis was performed using the statistical program SPSS version 25. Results: The means of variables, body mass index, waist circumference, waist height ratio, hip waist ratio, triglycerides, HDL-C, LAP, insulin, glycemia and HOMA-RI, in addition to the prevalence of overweight and central adiposity were higher in the group with insulin resistance. The LAP presented a higher correlation (r = 0.44) with the HOMA-RI and the larger area under the ROC curve (0.75) than the anthropometric indicators evaluated. Conclusion: Given its low cost, reproducibility, and greater discriminatory power against anthropometric indicators, LAP can be used as a screening tool for adolescents with insulin resistance.