Insight of the 2019 novel coronavirus: the epidemic and its challenges

Objective: According to the world health organization, the novel coronavirus(2019-nCoV) is declared as a pandemic on 30th January 2020 and is considered to be highly contagious concerning the public health emergency of international concern (PHEIC). The novel coronavirus emerged asan outbreak in China which was followed by other 29 countries. The expansion of the novel human respiratory coronavirus known as SARS-COV-2[severe acute respiratory syndrome coronavirus2] COVID-2019[coronavirus disease 2019] has stressed towards its therapeutic needs to reduce and cease further progression of this pandemic. This review aims to provide a summary of clinical signs and symptoms of novel Betacoronavirus infection and to demonstrate its the rapeutic conclusion for patients who may require antimicrobial treatment. Methods: From the present literature of microbiological infections, the article was reviewed and confirmed by 2019-conV[COVID-19] happened at the time of writing[13 February 2020]. Using the PubMed database and the Cochrane library literature study was carried out by using terms like “novelcoronavirus” or “2019-nCoV” or ‘The COVID-19”. Results: According to published manifestation, the majority of the cases were seen in males of age group ranging from 8-92. The endocrinal, Cardiovascular, digestive systemand the diseases related to such systems were commonly reported. However, the chronic pulmonary disease (for example, COPD, bronchitis, and asthma) were astonishingly underreported. Moreover, a series of cases were reported with common signs and symptoms such as fever, dyspnoea, flanked by myalgia, cough, and fatigue. However, fever was noticed in all of the cases. The most commonly reported radiological features of 2019-nCoVnoticed were bilateral ground-glass opacities, multiple bilateral lobular, and segmental areas of the lungs in the initial phase of the virus. Conclusion: Patients with positive coronavirus infection are mainly linked with respiratory disease and extrapulmonary signs and symptoms. However, there are fewer chances of pre-existing respiratoryrelated concomitants.