Glycolysis is starting part of the membrane redoxy potential three state dependent 9 stepped full cycle of proton conductance in the human body
International Journal of Development Research
Glycolysis is starting part of the membrane redoxy potential three state dependent 9 stepped full cycle of proton conductance in the human body
Article History: Received 18th October, 2020; Received in revised form 29th November, 2020; Accepted 17th December, 2020; Published online 30th January, 2021.
Copyright © 2020, Ambaga et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Glycolysis and the membrane redoxy potential three state dependent 9 stepped full cycle of proton conductance, described by us have a strong interconnection in the transferring of electron and protons, creation of proton gradient, ATP, NADH. The inner mitochondrial membrane is impermeable to NADH formedduring glycolysis, followed by Krebs cycle but by using two “shuttles” to transport the electrons from NADH across the mitochondrial membrane as the malate-aspartate shuttle and the glycerol phosphate shuttle, the malate then traverses the inner mitochondrial membrane into the mitochondrial matrix, where it is reoxidized by NAD+ forming intra-mitochondrial oxaloacetate and NADH+, which are very important parts of reaction medium as “Donators + membrane - redox potentials three - state line system + O2 + АDP + Pi + H+ + nH + membrane space = (ATP + heat energy) + H2O + nH + matrix + CO2” which is belong to the membrane redoxy potential three state dependent 9 stepped full cycle of proton conductance, described by us. The glycerol phosphate shuttle of electrons, protons formed during the glycolysis followed by Krebs cycle takes place on the inner mitochondrial membrane, allowing FADH2 to donate its electrons directly to coenzyme Q (ubiquinone) which is part of the electron transport chain have been participated in transferring of the electrons to molecular oxygen (O2), with the formation of water, also in releasing of energy eventually captured in the form of ATP, which are also inseparable parts of reaction medium as “Donators + membrane - redox potentials three - state line system + O2 + АDP + Pi + H+ + nH + membrane space = (ATP + heat energy) + H2O + nH + matrix + CO2” which is belong to the membrane redoxy potential three state dependent 9 stepped full cycle of proton conductance having a closed loop figure.