Epidemiology of vulvar cancers in the oncology- radiotherapy department of uhc/jra (madagascar)

Introduction: The incidence of vulvar cancer tends to increase in developed countries, particularly in younger women. Few studies about this disease have been done in our country. Our study aims to describe the epidemiological, clinical and therapeutic profile of vulvar cancers in the Oncology-Radiotherapy Department of the University Hospital Center Joseph Ravoahangy Andrianavalona (UHC/JRA), Antananarivo Madagascar. Method: This was a retrospective and descriptive study from January 2008 to December 2015. All patients with vulvar cancers histologically proven were included. Results: We collected 32 cases of vulvar cancers, including women from 29 to 80 years old, with a mean age of 53.81 years. Patients from Analamanga represented 75%, and post-menopausal women represented 41% of the study population. Tumors over 2 cm in size were found in 71.88% of the cases, with a predominance of an ulcerated appearance (43.8%). Squamous cell carcinoma is the most common histological type (66%). More than 50% of the cases were diagnosed at the localised stage. Only 20 women received specific treatment, in which 8 had surgery combined with chemotherapy. Among the women who were treated, 9 patients had a remission after 1 month of treatment. Conclusion: Our recruitment of vulvar cancers was low. A multicentric study will estimate the actual impact in Madagascar.