Effects of 7.5% polydextrose in blood levels and determinations of bone minerals in wistar gastrectomymized rats

The objective of this study was to evaluate the effects of polydextrose (PDX) supplementation on blood mineral levels and bone mineral composition in gastrectomizedwistarrats. Male Wistarrats (n = 40) with approximately 250 g underwent gastrectomysurgeryt o Billroth II with anterior truncalvagotomy, being distributed in two groups: gastrectomized (GXT) and false gastrectomized (SHAM). After seven post operative days were subdivided into four groups: SHAM Control (SHAM without polydextrose); SHAM PDX (SHAM with polydextrose); GXT Control (Gastrectomized without polydextrose); GXT PDX (Gastrectomized with polydextrose). Weight gain and diet in take were evaluated weekly. The animals were euthanized after 60 days. The animals in the SHAM control group had greater weight gain in comparison to the other groups. PDX maintained serumcalcium levels (calcium, phosphorus) in the groups supplemented with the prebiotic. Regarding phosphatase, the GXT PDX group presented higher averages, positively influencing the process of bonemineralization. The gastrectomy did not generate bone involvement in the studied groups GXT Control and GXT PDX and there was no difference with the groups SHAM Control and SHAM PDX. It can be concluded that PDX interferes positively in the maintenance of serum calcium and phosphorus levels with preservation of bonet issue.