Cytokines storm and sepsis: Prevalence in the Covid–19
International Journal of Development Research
Cytokines storm and sepsis: Prevalence in the Covid–19
Article History: Received 14th October, 2020; Received in revised form 03rd November, 2020; Accepted 22nd December, 2020; Published online 30th January, 2021.
Copyright © 2021, Caroline Nascimento Santos, Íris Ricardo Rossin, Giulia D’Alessandro Sanzovo and Mirella de Freitas Daud. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
In December 2019, a new betacoronavirus (SARS-CoV-2) was identified as the source of COVID-19. This viral infection with systemic repercussions requires hospitalization of a huge number of patients with high mortality. In many cases, there is a dysregulated inflammatory response triggered by a phenomenon called a cytokine storm, which leads to life-threatening multiple organ dysfunctions, known as sepsis. Respiratory, cardiac and tissue perfusion functions are severely impaired in these individuals. The loss of those vital functions is related to the pathophysiology of this syndrome with tragical morbidity and mortality.
