Comparative study on poly cystic ovarian syndrome in normal, overweight and obese women of selected population
International Journal of Development Research
Comparative study on poly cystic ovarian syndrome in normal, overweight and obese women of selected population
Received 19th September, 2017; Received in revised form 26th October, 2017; Accepted 29th November, 2017; Published online 30th December, 2017.
Copyright ©2017, Velvizhi and Annapurani. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Objectives: To investigate the levels of C- reactive protein, liver enzymes and TBARS levels in the women with Polycystic Ovary Syndrome (PCOS) and controls divided according to body mass index (BMI) and their association with features of this syndrome. Methods: Twenty one PCOS women and 10 healthy women were studied. Patients and controls were subdivided into three groups, Group 1 Healthy women with BMI 18.5- 24.99(n=10), Group 2 PCOS with BMI 25-29.9(n=11) and Group 3 PCOS with BMI >29.9(n=10).Clinical history, height and weight were obtained from the participants. Results: Serum CRP, Plasma TBARS, and liver marker enzymes were significantly elevated in both overweight and obese PCOS compare to normal healthy women. Conclusion: An increase in oxidant status, inflammatory response and liver marker enzymes was found in women with PCOS, and this increase was related to Body mass Index.
