Clinical characteristics and outcomes among Brazilian patients with HIV/SARS-COV-2 coinfected: An observational retrospective study

Background: Patients with human immunodeficiency virus (HIV) infection be capable of a high risk for mortality from the coronavirus disease 2019 (COVID‐19). We present the clinical outcomes of HIV patients hospitalized for COVID‐19. Methods: We conducted a retrospective cohort study of HIV patients admitted for COVID‐19 between January 2021 and August 2021 to Hospital Municipal Ronaldo Gazolla. Data on baseline clinical characteristics, computed tomography of the chest, and outcome. Results: During the study period, 40 HIV patients were admitted for COVID‐19, and 9 were excluded for not meeting the eligibility criteria. 67.7% are male and 10 32.3% are female. The COVID- 19 tests for RT- PCR (51.6%) and Antigen Test (29.0%).The comorbid included hypertension (17%), obesity (2,7%), or diabetes mellitus (5,7%). The O2 supply was nasal O2 cannula (73,3%), high flow nasal (10%), and mechanical ventilator (6,67%), and no use oxygen was 10%. A total of 32% of HIV patients were hospitalized with outcomes of death, and 25 (75,76%) was a survivor. In the findings of chest CT images, ground-glass opacity was more expressive at 29.0% have 25-50%. Conclusion: Data on the association of human immunodeficiency virus (HIV) infection with adverse outcomes in patients with COVID-19 are conflicting in the literature. Our findings suggest that patients with HIV have an increased risk of hospital admission for COVID-19, but especially in Hospital Ronaldo Gazolla outcome is survival for these patients.