Chronic use of proton-pump inhibitor: A Narrative Review
International Journal of Development Research
Chronic use of proton-pump inhibitor: A Narrative Review
Received 18th July, 2018; Received in revised form 14th August, 2018; Accepted 29th September, 2018; Published online 30th October, 2018
Copyright © 2018, Edenilson Cavalcante Santos et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Proton-pump inhibitors (PPIs) are one of the most prescribed therapeutic classes in the world, among them, omeprazole is found in the Brazilian essential drug list. Some research papersshow that the short-term use of PPIs can be safe, although its long-term use may cause adverse effects.The present review aimed to gather papers related to the effects of chronic use of PPIs in the literature. It is a narrative review in which the research for data was carried out in the Virtual Health Library in September 2018. The articles selected to compose the sample revealed that PPIs are used empirically for extended period beyond what is recommended and sometimes as self-medication. It is urgent the adoption of strategies by healthcare managers and prescribing professionals of all levels of attention to fight against inadequate prescription and chronic use. Therefore, as a result of that, promoting prevention of damages to the population and unnecessary expenses to the Brazilian public health system.
