Characterization of estrous cycle phases in rats (Rattus norvegicus) by vaginal smear
International Journal of Development Research
Characterization of estrous cycle phases in rats (Rattus norvegicus) by vaginal smear
Received 16th August, 2021 Received in revised form 26th September, 2021 Accepted 20th October, 2021 Published online 28th November, 2021
Copyright © 2021, Danniel C. L. Ferreira et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The determination of the estrous cycle in animals is important for studies of neuroendocrine function. The objective was to provide the researchers with the morphological characteristics of each phase of the estrous cycle in rats in. Proestrus is characterized by the predominance of a large number of round nucleated globular cells; in the estrus has identification of anucleated and conified epithelial cells; the next phase metaestrus has an equivalent proportion of nucleated and anucleated epithelial cells. The last phase is characterized by thin vaginal mucosa with predominance of leukocyte cells and presence of nucleated and round cells.
