Calophyllum brasiliense cambess (jacareúba) extract: effects under rats skin wound healing
International Journal of Development Research
Calophyllum brasiliense cambess (jacareúba) extract: effects under rats skin wound healing
Received 20th December, 2020; Received in revised form 17th January, 2021; Accepted 10th February, 2021; Published online 15th March, 2021
Copyright © 2021, Tarcisio Vitor Augusto Lordani. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Objective: To evaluate the healing activity of a crude extract of C. brasiliense on cutaneous wounds in rats. Method: adult male rats were wounded and randomized in three groups, where each one of those have received different topical treatment: 0.9% Saline Solution; Base Gel and Base Gel with crude extract of Callophylum brasiliense Cambess 2%. Morphometric and morphological analyses were performed at 7 and 14 days after topical treatment. Results: the animals topical treated with Base Gel with crude extract of Callophylum brasilienseCambess 2% had improved the closure wound, angiogenesis, and the collagen fibers type I and III content. Conclusion: topical treatment with the base gel containing crude extract of C. Brasiliense 2% can modulate the different phases of the wound healing process, showing the high potential of this herbal medicinal as healing.
