Assessment of Vitamin D serum levels in patients with oral lichen planus
International Journal of Development Research
Assessment of Vitamin D serum levels in patients with oral lichen planus
Received 17th December, 2023; Received in revised form 21st December, 2023; Accepted 10th January, 2024; Published online 30th January, 2024
Copyright©2024, Dr. Priyanka Raghav et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background: This study was conducted to compare Vitamin D Serum Levels in Patients with Oral Lichen Planus and Healthy Subjects. Material and methods: There were 20 subjectsincluded in the study, diagnosed with Oral Lichen Planus and 20 subjects without the condition. Vitamin D serum levels was measured in both Oral Lichen Planus subjects and healthy controls after collecting 5 mL of blood from each group and analysing it with a vitamin D total (25-hydroxy vitamin D) kit using the electrochemiluminescence technique. Patient consent form were taken and recorded. The independent samples t-test or its non-parametric alternative was used to examine the data in SPSS 17. The cutoff for statistical significance is p<05. Results: 20 subjects were evaluated in the control group, consisting of 16 females (80%) and 4 males (20%) subjects. In the OLP group, 20 patients were evaluated, consisting of 15 females (75%) and 5 males (25%) subjects. Differences in vitamin D levels between the OLP and control groups were larger in the healthy subjects, with a mean difference of 6.4 units (ng/mL) between the two groups, but statistically using an independent t-test no significant differences were found between the two groups because of the homogeneity of variances in the two groups as verified by the Levene's test. Conclusion: Serum vitamin D levels in those with oral lichen planus were not significantly different from those in healthy people.