Antimicrobial and antibiofilm of aloe vera on bacteria

Objective: This study aimed to evaluate the antimicrobial and antibiofilm potential of 10% Aloe vera gel against in vitro oral bacteria compared with 2% Chlorhexidine Gluconate gel. Design: The antimicrobial activity was evaluated using radial diffusion and agar perforation. The results were identified by the presence and visual size of the halo of inhibition of the bacterial growth around the holes. The microbial biofilm formation assay was conducted in 24-well surface-modified polystyrene plates with flat bottom. All experiments were performed in triplicate with the respective results categorized and further statistical analysis in software GraphPad Prism. For the analysis of intergroup differences, ANOVA with Bonferroni post-test and significance level of 1% were performed. Results: The 10%Aloe vera gel presented antimicrobial activity against all the oral bacteria analyzed and such activity was greater than that of the 2% Chlorhexidine Gluconate gel against some strains. The antibiofilm potential did not significantly affect the oral bacteria analyzed, with similar results observed for all the strains. Conclusions: The elucidation and analysis of the results of the present study demonstrated the antimicrobial activity of the 10% Aloe vera gel against all the oral bacteria analyzed. However, the antibiofilm potential of the 10% Aloe vera gel did not significantly affect the oral bacteria tested.