Anti-inflammatory and antipyretic activity of curcuma longa l. collected from Uttarakhand

The plant extracts of Curcuma longa L., a perennial herb is a member of the Zingiberaceae (ginger) family. The methanolic extracts were investigated for its anti-inflammatory and antipyretic activities in animal models. The extract at different doses used showed good anti-inflammatory activity which has been done significantly, by the formation of paw edema induced by carrageenan model. Anti-inflammatory effects of plants were monitored every hour after carrageenan injection. These results were also comparable to Indomethacin, the reference drugs used in this study. In antipyretic activity paracetamol is used as reference drug. Result showed that the methanolic extract collected from the Ukhimath (100mg/kg body wt) showed better result as compared to Haldwani extracts, which might be because of climatic, edaphic and genetic variation.