A systematic review of aging and its causes
International Journal of Development Research
A systematic review of aging and its causes
Received 17th August, 2018; Received in revised form 09th September, 2018; Accepted 21st October, 2018; Published online 28th November, 2018
Copyright © 2018, Fayyaz Madiha et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Aging is the accumulation of detriment which may lead to decline in normal function on cellular, tissue and organ level that ultimately causes age-related diseases and death over time. Genetics, intrinsic (endogenous) and extrinsic (environmental) factors play potential role in complex process of aging. Aged skin shows abnormalities in angiogenesis, immune system, vitamin D synthesis, wound healing and sweat and lipid production causing benign and malignant cancers. The ongoing overview uncovers the relationship between intrinsic and extrinsic skin aging processes. The effect of shortening of telomeres during every cell division is also a factor to determine skin aging. Natural products have been the essential source of medicines since ages. The purpose of skin anti-aging is to slow, cease or reverses the process of aging just to expand the life span of skin of individual. Many natural products from plant extracts and animal by-products have been employed as anti-aging agents in commercially available products.
