Use of fluoxetine in depression treatment

This study aimed to analyze the current literature approaches to the use of fluoxetine in the treatment of depression. It is an article based on bibliographical research published between the years of 2002 to 2018. A total of 70 studied contents were included, and after selective and meticulous reading, 19 papers and two dissertations were submitted to compose this review. It can be seen that depression is one of the most growing mental disorders in the population that can be identified by feelings of sadness, decrease or loss of interest in almost all daily activities. Its neurobiological causes are based on the monoaminergic hypothesis that follows the idea that depression is caused by a decrease in brain biogenic amines, serotonin, noradrenaline and / or dopamine. According to the selected articles, it can be evidenced that although there is a great variety of drugs available for the treatment of this pathology, the most used among them is fluoxetine, belonging to the class of antidepressants Selective Serotonin Reuptake Inhibitors, be considered to be more effective than the Monoaminoxidase Tricyclic antidepressants and Inhibitors because they have a once daily dosage, acceptable adverse effects, high tolerability, relative cardiovascular safety and a comparatively favorable cost.