Morphometric analysis of the effect of royal jelly on the vasospastic femoral artery in rats: An experimental study

This study aimed to examine the efficacy of royal jelly, which has potent anti-inflammatory and antioxidant properties, on the vasospastic femoral artery in rats. In total, 24 Wistar- albino strain rats were divided into three groups: group 1, control (n = 8); group 2, vasospasm (n = 8) and group 3, vasospasm + royal jelly treatment (n = 8). The wall thickness (W) of the femoral arteries and the luminal diameters (L) were morphometrically measured. Data were analyzed using the SPSS software. Statistical significance was set at an alpha level of p < 0.05. The mean L values were significantly lower in group 2 than in groups 1 and 3 (p = 0.001, for all). In addition, the mean L values were significantly lower in group 3 than in group 1 (p = 0.001, for all). The mean W values were not significantly different between groups 1 and 3 (p = 0.325). The mean W values were statistically significantly higher in group 2 than in groups 1 and 3 (all p < 0.001). The statistical analysis of our results suggested that royal jelly can effectively prevent vasospasm because of its anti-inflammatory and antioxidant properties.