Primitive neurectodermal tumour in young adults – a report of 2 rare cases and review of literature
International Journal of Development Research
Primitive neurectodermal tumour in young adults – a report of 2 rare cases and review of literature
Received 29th August 2017; Received in revised form 20th September, 2017; Accepted 22nd October, 2017; Published online 30th November, 2017
Copyright ©2017, Dr. Vidhya Lakshmi and Dr. Thirumurthy. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Primitive Neurectodermal tumours are a group of malignant neoplasms of presumed neural crest origin previously termed as “Neuroepithelioma”.They are small round blue tumours which are sub classified based on differentiation and occurs mostly in brain and very rarely in the spinal cord. We report two cases of primitive neurectodermal tumour in young adult female patients. One is in the spinal cord of a young female and another is a primitive neurectodermal tumour with neuroglial differentiation. The diagnosis was made based on the morphological and immunohistochemical examination. These tumours have a highly aggressive clinical course with a poor outcome in spite of multimodality treatment options. The other case was a primitive neurectodermal tumour with neuroglial differentiation which imparts a poor prognosis.
