Determinants of in-hospital mortality of covid-19 among 2954 inpatients in a private hospital network in the metropolitan region of belo horizonte

Background: The COVID-19 pandemic brought challenges to different health systems around the world. Brazil was not spared. Information on the demographic characteristics of patients and their evolution are essential for coping with large numbers of patients. Methods: This retrospective cohort of 2954 patients with COVID-19 admitted to the Rede Mater Dei de Saúde Network, Belo Horizonte, Brazil, between March 21, 2020 and June 22, 2021 assessed demographic and clinical data as well as the use of therapeutic resources and mortality. Results: Our samples included 2954 patients, predominantly male (62.1%). The mean age of patients was 58.2 ± 17.5 years, it was found that increasing age was related to increased mortality. The overall mortality was 13.7%, and evaluations in a multivariate analysis, including: age (HR:1.074, CI:1.060-1.089, p=0.0001), systemic arterial hypertension (HR:1.595, CI:1.074-2.369, p=0.021), diabetes (HR:1.589, CI:1.092-2.312, p=0.016), increased respiratory rate (HR:1.053, CI:1.020-1.087, p=0.001), CRP (HR:1.012, CI:1.011-1.014, p=0.0001), TGO (HR:1.004, CI:1.001-1.007, p=0.006), lactate (HR:1.039, CI:1.007-1.072, p=0.015), total leucocytes (HR:1.356, CI:1.152-1.596, p=0.0001) and platelet count (HR:0.465, CI:0.366-0.593, p=0.0001), were able to predict the prognosis. Conclusions: There is a high mortality in patients hospitalized due to COVID-19, the presence of comorbidities, and age significantly increases mortality and the use of resources in the hospital.