Evaluation of Antibiotic effects in Hospitalized Patients with Urinary tract Infection: A Cross-Sectional Investigation

Objective: To identify predominant UTI-causing microorganisms in hospitalized patients, assess antibiotic effects on prognosis and hospital stay, and find favorable antibiotic alternatives for UTI management. Methods: We conducted a cross-sectional study of 189 adult UTI patients. Data on demographics, laboratory results, antibiotics, and hospital stays were collected. Stringent inclusion criteria were used. Multiple regression and statistical tests assessed hospitalization factors. Results: In the 18-95 age range, women showed a greater prevalence of UTIs (52.4%) than males (47.6%). The most common urine isolated microorganism was Escherichia coli (33.3%). High neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) (5.324 ± 3.055 and 174.979 ± 70.687) were detected. Carbapenems (5.92 days, 95% CI [0.271; 1.403]) were related with longer hospital stays than cephalosporins (3.98 days, 95% CI [-1.88; -1.124 The study's model described 48% of hospital stay duration variance (R²=0.48, RMSE=0.19, p<0.001). Conclusion: UTIs were found to be more common in women. The most common isolate (33.3%) was E. coli. Higher NLR and PLR levels show that inflammatory markers may be utilized as a clinical judgment of infection in patients. Cephalosporins were associated with shorter hospital stays (3.98 days) compared to quinolones (4.88 days) and carbapenems (5.92 days), indicating they may be a more effective antibiotic choice for UTIs to reduce hospitalization.