Characterization of breast cancer survivors regarding adverse effects and lifestyle during hormone therapy with tamoxifen
International Journal of Development Research
Characterization of breast cancer survivors regarding adverse effects and lifestyle during hormone therapy with tamoxifen
Received 20th February, 2021; Received in revised form 17th March, 2021; Accepted 03rd April, 2021; Published online 14th May, 2021
Copyright © 2021, Maria Lúcia Souza Siqueira et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Objective: to carry out a study with women diagnosed with breast cancer and under hormone therapy with Tamoxifen (TAM) and to represent the adverse effects and the lifestyle of the patients, as well as their sociodemographic and therapeutic characteristics in a public oncology hospital of Brazil. Methodology: exploratory, descriptive and quantitative study whose population was composed of women (n = 20) under hormonal treatment. For evaluation, a questionnaire to obtain socio-demographic, therapeutic, anthropometric, lifestyle and adverse effects data was applied and the Excel and BioStat 5.0 programs were used to analyze the results. Results: Brown women between 40 and 45 years old, self-employed and commercial, income from 1 to 3 minimum wages, married and in stable union, in the pre and post-menopause, with grade II ductal carcinoma, submitted to chemotherapy and radiotherapy, in treatment with TAM for 2 to 3 years, make up the profile of patients. Gynecological and vasomotor complications comprise the adverse effects that are the most troublesome such ashot flushes, irritation, itching and vaginal bleeding followed by mood changes, body weight gain, gastrointestinal intolerance, visual disturbances and to a lesser extent memory lapses, depression, lipid changes, hepatic and endometrial. Sedentary lifestyle favored overweight and obesity. Conclusion: patients in climacteric undergoing hormonal treatment with TAM, presented adverse effects suggestive of estrogen deficiency exacerbated by the use of the drug with negative variables for overweight and obesity and should be warned about the possible adverse effects of anticancer treatments, providing options for therapeutic choices that best suit the profile.